Pharmacology

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Question

This question has been answered by 21 people and has an average rating of 3.83 (based on 18 ratings)

A 35 year old male patient recently has arrived in the ER with complaints of pain radiating between his navel and breastbone along with black tarry stools. The patient had recently lost his job 6 months prior and has been a heavy smoker for the last 15 years. Through an endoscopy, the doctor finds that the patient has a stress and smoker induced duodenal ulcer. A rapid urease test was done to rule out an H.Pylori infection. What medication DOES NOT need to be prescribed to the patient for treatment and healing of his duodenal ulcer? 

Alternatives

The contributor suggests D is the correct option
Option Alternative First
answers
Confirmed
answers
A

Mylanta (Antacids)

3 (14.29%)

0 (0.00%)

B

Omeprazole (Proton Pump Inhibitors (PPIs))

1 (4.76%)

0 (0.00%)

C

Misoprostol (Synthetic Prostaglandin E)

4 (19.05%)

0 (0.00%)

D

Amoxicillin (Antimicrobrials) 

13 (61.90%)

8 (100.00%)

E

Ranitidine (Histamine H2 Receptor Antagonists (H2RAs))

0 (0.00%)

0 (0.00%)

Explanation

The following explanation has been provided relating to this question:

A - antacids are prescribed to relieve abdominal discomfort. they neutralize gastric acid and decrease pepsin production in the stomach. they are usually not sufficent to heal a peptic ulcer as a single therapy but are used to relieve abdominal discomfort. this drug would be beneficial to the patient. 

B - PPIs are prescribed because they are strong inhibitors of gastric acid secretion, they provide faster symptom relief and faster healing rates for peptic ulcers. this drug would be beneficial to the patient. 

C - misoprostol inhibits gastric acid secretion. increases mucous and bicarbonate decretion, and enhances mucosal blood flow and repair. this would be beneficial to ulcer healing for the patient. 

D - antimicrobrials are prescribed to eradicate H pylori infections, since the h pylori infection was ruled out for the patient, there is no need for antimicrobrials.

E - H2RAs can be prescribed to block histamine H2 receptors. they act as a partial agonist at gastrin and acetylcholine receptors to reduce pain associated with peptic ulcers, promote healing of the ulcer, and reduce the risk of ulcer reoccurrence. This drug would be beneficial to the patient. 

 

Topics

The following topics have been indicated as being relevant to this question:

peptic ulcer disease

Comments

There are 19 comments for this question (10 top-level comments and 9 replies) 
Written: 10:40pm, 13 DecAuthor has: 3687 points and 22 badges

An excellent thorough explanation to your answer. And also an extremely well written question. Keep up the good work :) I really enjoy your questions. 

 Written: 10:47pm, 13 DecReply written by question author
 

Thanks for the feedback :) 

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Written: 10:44pm, 13 DecAuthor has: 4018 points and 21 badges

Excellent way of incorporating amoxilin into a case scenario!

 Written: 10:47pm, 13 DecReply written by question author
 

Thank you!

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Written: 10:46pm, 13 DecAuthor has: 1607 points and 8 badges

Great question and explanations!

 Written: 10:47pm, 13 DecReply written by question author
 

Thank You!

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Written: 1:04pm, 14 DecAuthor has: 2699 points and 14 badges

Great scenario type question! Your explanation was very clear and comprehensible. 

 Written: 2:57pm, 14 DecReply written by question author
 

Thanks :) 

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Written: 6:16pm, 15 DecAuthor has: 3393 points and 16 badges

You're explanation really helped me fully understand the concept fully without any questions! 

 Written: 2:53pm, 17 DecReply written by question author
 

thank you!

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Written: 7:48am, 14 DecAuthor has: 6616 points and 21 badges

Good clinically relevant question with excellent explanation!

 Written: 8:38am, 14 DecReply written by question author
 

Thank You :)

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Written: 8:36am, 14 DecAuthor has: 2617 points and 16 badges

Really great job explaining each medication and its uses in the answer, thank you! Great question

 Written: 8:38am, 14 DecReply written by question author
 

Thank you :) 

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Written: 2:14pm, 14 DecAuthor has: 6961 points and 25 badges

Very good question! It helped solidify my understanding of drugs for peptic ulcer disease!

 Written: 2:57pm, 14 DecReply written by question author
 

Thank You!

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Written: 2:41pm, 14 DecAuthor has: 3344 points and 12 badges

good question! After having gone through my notes and getting the question wrong the first time, I now understand the concept much better. good job!

 Written: 2:57pm, 14 DecReply written by question author
 

awesome, thank you :) 

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Written: 5 hours agoAuthor has: 1909 points and 16 badges

Great question and explanation! Well done!

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